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Cocktails, tablets, capsules, and individual purified formulations of protease inhibitors and phosphatase inhibitors designed to protect proteins from degradation during cell lysis and extraction.
The HDL Receptor SR-BI Inhibitor, BLT-1, also referenced under CAS 321673-30-7, controls the biological activity of HDL Receptor SR-B. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
Histone Acetyltransferase p300 Inhibitor, C646, CAS 328968-36-1, is a cell-permeable, reversible inhibitor of p300/CBP HAT (Ki = 400nM). Competes with acetyl-CoA for the p300 Lys-CoA binding pocket.
The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
The Neurotrophin Antagonist, Y1036 controls the biological activity of Neurotrophin. This small molecule/inhibitor is primarily used for Neuroscience applications.
The MK-2 Inhibitor IV, MK-25 controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Phosphatase Inhibitor Cocktail Set I contains three inhibitors that will inhibit alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A.
A cell-permeable purine compound that binds ARFGAPs (Kd = 364 and 620 nM for AMAP1 and ARFGAP1, respectively) and acts as a broad specificity ARFGAPs inhibitor (GTPase activating proteins of ADP-ribosylation factor).
The PAF Receptor Antagonist, ABT-491, also referenced under CAS 189689-94-9, controls the biological activity of PAF Receptor. This small molecule/inhibitor is primarily used for Membrane applications.
A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).